Dr. St. Germain was appointed Director of MMCRI and VP for Research at Maine Medical Center in 2009. He received a B.S. degree (magna cum laude) in Chemical Engineering from Louisiana State University in 1972 and subsequently attended the Johns Hopkins University School of Medicine, where he received the M.D. degree in 1976. He completed his clinical training in Internal Medicine and Endocrinology at University Hospitals of Cleveland in 1980, and subsequently served as Chief Resident in Internal Medicine at Dartmouth-Hitchcock Medical Center (DHMC).

In 1981, he undertook a postdoctoral research fellowship in the Departments of Medicine and Physiology at Dartmouth Medical School where he trained with Dr. Valerie Anne Galton and Dr. Robert Adler. He was appointed to the faculty of Dartmouth Medical School in 1984.

Dr. St. Germain’s research program has centered on investigating the molecular mechanisms involved in the metabolism and action of thyroid hormones, with a particular focus on the developmental and neurological effects of these native compounds. In this regard, Dr. St. Germain and his colleagues have developed and are studying a number of transgenic mouse lines with altered expression of the deiodinase enzymes, which regulate thyroid hormone levels during fetal and neonatal life. 

In addition to his research efforts, Dr. St. Germain was actively involved in teaching and organizing several basic science and clinical courses at Dartmouth Medical School, and was the Director of the Dartmouth Community Medical School public education initiative.  He is a former and current ad hoc member of the NIH Endocrinology Study Section, and maintains a consultative practice in general endocrinology with an emphasis on evaluating patients with thyroid disorders.

Dr. St. Germain served as Interim Chair of the Department of Medicine at Dartmouth Medical School from 2001 – 2003 and was a member of the DHMC Board of Governors from 2008 – 2009.  He is the recipient of the Dean’s Award from Dartmouth Medical School in 2003 for “contributions to our missions of excellence in scholarship, clinical care, education and service” and was awarded the Clinical Sciences Teaching Award from the Dartmouth Medical School Class of 2005.

Since being recruited to Maine Medical Center, Dr. St. Germain has overseen an expansion of research activities across the organization, including the institution of novel programs to support and foster translational and clinical research programs that are benefiting the patients of Maine and strengthening the academic stature and the national visibility of the institution.